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You are here:Home » Antibodies » Abs to Enzymes, Phospholipase » Anti -PLCg2 (Phospholipase C, gamma 2, 1-phosphatidylinositol-4,5-bisphosphate Phosphodiesterase gamma-2, Phosphoinositide Phospholipase C-gamma-2, Phospholipase C-IV, PLC-IV, Phospholipase C-gamma-2, PLC-gamma-2, PLCG2)

Anti -PLCg2 (Phospholipase C, gamma 2, 1-phosphatidylinositol-4,5-bisphosphate
Phosphodiesterase gamma-2, Phosphoinositide Phospholipase C-gamma-2, Phospholipase C-IV,
PLC-IV, Phospholipase C-gamma-2, PLC-gamma-2, PLCG2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
PLCg2 gene encodes an enzyme that plays a crucial role in intracellular signal transduction pathways. This enzyme is important because of its role in the generation of second messengers following the hydrolysis of phosphatidylinositol 4,5-bisphosphate. Human PLCg2 gene maps to the long arm of human chromosome 16, in the region q22-qter. The protein contains 2 SH2 and 1 SH3 domains through which they can interact with other signaling proteins, suggesting adapter function. The protein is primarily limited to cells of hematopoietic lineage.
Catalog #P4074-45Q
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlA431 cells
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic non-phosphopeptide corresponding to human PLCg2 around the phosphorylation site of tyrosine 753 (S-L-YP-D-V).
SpecificityRecognizes human PLCg2. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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