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You are here:Home » Antibodies » Abs to Amino Acids » Anti -Phosphothreonine Proline

Anti -Phosphothreonine Proline

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Phosphothreonine-Proline, along with similar motifs involving serine/threonine residues preceding proline undergoing phosphorylation, has critical roles in the moderation of various cellular processes, protein function, and kinases through proline-directed phosphorylation. The deregulation of proline-directed phosphorylation is known to be a factor in diseases such as cancer and Alzheimer’s neurodegeneration.
Catalog #P4077-51
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlCalyculin treated Jurkat cell lysate.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in TBS, 0.05% sodium azide, 50% glycerol.
PurityPurified by ammonium sulfate precipitation.
ImmunogenPhosphothreonine-proline amide (pT-P-NH2) peptide conjugates (KLH).
SpecificityRecognizes human Phosphothreonine-Proline motif. Species crossreactivity: rmouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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