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Specifications

Clone Host Grade Applications Monoclonal Mouse E B IP IC

Protein tyrosine phosphorylation has been the subject of intense investigation for over two decades. Tyrosine phosphorylation is catalyzed by members of the tyrosine kinase superfamily. To date, approximately 90 members of this superfamily have been identified in the human genome. Levels of phosphorylation of tyrosine residues within cellular proteins are observed to increase in response to growth factors, cytokines, insulin, extracellular matrix components, and other stimuli. Tyrosine phosphorylation has several effects, including the regulation of enzyme activity, as well as the localization of enzyme activity through the generation of docking sites for proteins bearing SH2 domains.
Catalog #	P4078-38
Application(s)
	ELISA
	Immunocytochemistry
	Immunoprecipitation
	Western Blot
	Optimal conditions must be determined individually for each application.
POSITIVE CONTROL INCLUDED
	Yes.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	6D670
Host	Mouse
Immunogen	Phosphotyrosine containing peptides.
Specificity	Recognizes phosphotyrosine in the context of the surrounding amino acids.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.