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You are here:Home » Biochemicals » Biochem-Antibiotics » Piericidin A (Shaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT 143D, Piericidin A1)

Piericidin A (Shaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT
143D, Piericidin A1)

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Specifications

Piericidin A is the major analogue of a family of pyridyl antibiotics isolated from selected Streptomyces sp. It is a specific, potent inhibitor of NADH-ubiquinone oxidoreductase (Complex I) that binds to ubiquinone binding site(s). Piericidin A inhibits both mitochondrial and bacterial NADH-ubiquinone oxidoreductases, binding close to NUOD-NUOB interface.
Catalog #P4155
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number2738-64-9
Molecular FormulaC25H37NO4
Molecular Weight415.6
SourceStreptomyces sp.
Purity~95% by HPLC
FormSupplied as a pale yellow oil. Soluble in ethanol, methanol, DMF or DMSO.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesShaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT 143D, Piericidin A1


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