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Anti -PIM1 (Serine/Threonine-protein Kinase Pim-1)
Anti -PIM1 (Serine/Threonine-protein Kinase Pim-1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH IF |
|
| Catalog # | P4186-60J | | PIM-1, an immediate early gene in the PIM subfamily of kinases, has been implicated in the regulation of proliferation, differentiation and cell survival of lymphoid and myeloid cells. PIM-1 is a cytoplasmic modulator of the interleukin-3 signal transduction pathway. Two isoforms of PIM-1 exist | the larger protein is an amino-terminal extension of the smaller protein and is synthesized by alternative translation initiation at an upstream CUG codon. | | Applications | Suitable for use in ELISA, Immunofluorescence and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunofluorescence: 10ug/ml | | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a,l | | Clone No | 3F5 | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Recombinant corresponding to aa1-314 from human PIM1 with GST tag. MW of the GST tag alone is 26kD. | | Specificity | Recognizes human PIM1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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