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You are here:Home » Antibodies » Abs to Oncoproteins » Anti -PIM1 (Serine/Threonine-protein Kinase Pim-1)

Anti -PIM1 (Serine/Threonine-protein Kinase Pim-1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH IF
Catalog #P4186-60K
PIM-1, an immediate early gene in the PIM subfamily of kinases, has been implicated in the regulation of proliferation, differentiation and cell survival of lymphoid and myeloid cells. PIM-1 is a cytoplasmic modulator of the interleukin-3 signal transduction pathway. Two isoforms of PIM-1 exist the larger protein is an amino-terminal extension of the smaller protein and is synthesized by alternative translation initiation at an upstream CUG codon.
ApplicationsSuitable for use in ELISA, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 10ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No6A2
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to aa1-314 from human PIM1 with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human PIM1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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