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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -Piwi-like Protein 1 (PIWIL1)

Anti -Piwi-like Protein 1 (PIWIL1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Piwi-like protein 1 is also known as PIWIL1 (Swiss Prot: Q96J94). It may be component of some RISC (RNA-induced silencing) complexes, which plays a role in spermatogenesis and in germ cell production, proliferation, and maintenance. RISC complexes mediate RNA cleavage and translational silencing. Overexpression may cause malignant germline development. PIWIL1 may be associated with proliferating activity of cancer cells. When suppressed, it can inhibit the growth of gastric cancer cells and induce cell cycle arrest in G2/M phase. It also inhibits endoribonuclease DICER1 activity.
Catalog #P4210-35
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.03-0.125ug/ml
Western Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityFor long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 30% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human Piwi-like protein 1. (KLH)
SpecificityRecognizes endogenous level of human Piwi-like protein 1. Species crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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