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You are here:Home » Antibodies » Abs to Coagulation Factors » Anti -Plasminogen Activator Inhibitor Type I (PAI-1)

Anti -Plasminogen Activator Inhibitor Type I (PAI-1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Plasminogen activator inhibitor-1 (PAI-1) is the principal inhibitor of urokinase plasminogen activator(uPA) and tissue plasminogen activator (tPA). It belongs to the group of serpins (serine protease inhibitors). Elevated levels of PAI-1 are associated with poor prognosis in many types of cancer.
Catalog #P4256-34F
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
ELISA: Can be used as a coating antibody for uPA:PAI-1 complex ELISA.
Optimal dilutions to be determined by the researcher.
HybridomaNCI-Ag 4/1 myeloma cells with spleen cells from Balb/c mice.
Culture MediumRPMI 1640 with 10% fetal calf serum
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG1
Clone No9B6
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenPartially purified human PAI-1
SpecificityRecognizes human PAI-1. No crossreactivity is observed with PAI-2. No reactivity is observed with any other human plasma protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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