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Anti -Plasminogen Activator Inhibitor Type I (PAI-1)
Anti -Plasminogen Activator Inhibitor Type I (PAI-1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH |
|
| Plasminogen activator inhibitor-1 (PAI-1) is the principal inhibitor of urokinase plasminogen activator(uPA) and tissue plasminogen activator (tPA). It belongs to the group of serpins (serine protease inhibitors). Elevated levels of PAI-1 are associated with poor prognosis in many types of cancer. | | | Catalog # | P4256-34F | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | | | ELISA: Can be used as a coating antibody for uPA:PAI-1 complex ELISA. | | Optimal dilutions to be determined by the researcher. | | Hybridoma | NCI-Ag 4/1 myeloma cells with spleen cells from Balb/c mice. | | Culture Medium | RPMI 1640 with 10% fetal calf serum | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 9B6 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Partially purified human PAI-1 | | Specificity | Recognizes human PAI-1. No crossreactivity is observed with PAI-2. No reactivity is observed with any other human plasma protein. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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