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You are here:Home » Antibodies » Antibodies-Coagulation Factors » Anti -Plasminogen Activator Inhibitor Type 1 (PAI 1)

Anti -Plasminogen Activator Inhibitor Type 1 (PAI 1)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH
Plasminogen Activator Inhibitor 1 (PAI-1) is a glycoprotein found in plasma that is implicated in the processes of angoigenisis, hemostasis, tumor metastasis, fibrionlysis, ovulation, embryonic development and inflammation. The elevation of PAI-1 has shown to correlate with the prognosis of many cancers including breast cancer. PAI-1 is activated by the glycoprotein vitronectin. Vitronectin binds to PAI-1 and modulates fibrinolysis and cell migration. This binding has proven to be an important inhibitor of the activated form of protein C (APC).
Catalog #P4256-34J
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: 10ug/ml
Optimal dilutions to be determined by the researcher.
HybridomaNSO cells with spleen cells from BALB/c mouse
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No5F119
Concentration~1mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS, pH 7.4, 0.02% sodium azide. Reconstitute with 500ul sterile ddH2O.
PurityPurified by Protein G affinity chromatography.
ImmunogenPAI from human melanoma cell line MJZJ.
SpecificityRecognizes human active PAI-1, latent PAI-1, inactive PAI-1 and t-PA-PAI-1 complexes. Does not recognize PAI-2 or PAI-3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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