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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -PAI-1 (Plasminogen Activator Inhibitor Type 1, SERPINE1, PAI, PAI1, PAI-1, PLANH1, Serine (or Cysteine) Proteinase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1, Plasminogen Activator Inhibitor, Type I)

Anti -PAI-1 (Plasminogen Activator Inhibitor Type 1, SERPINE1, PAI, PAI1, PAI-1, PLANH1,
Serine (or Cysteine) Proteinase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor
Type 1), Member 1, Plasminogen Activator Inhibitor, Type I)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
PAI-1 is a 45kD serine protease inhibitor which is the principle inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA). Plasminogen activator inhibitor-1 is also known as Serpine1, and due to its inhibitor function of tPA and uPA, is an inhibitor of fibrinolysis. PAI-1 is present at increased levels in various disease states, and has been linked to an increased occurrence of thrombosis in obesity and the metabolic syndrome. Defects in serpine1 are characterized by abnormal bleeding.
Catalog #P4256-34P
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in tris-saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding tointernal region of PAI-1 (NP_000593.1).
SpecificityRecognizes epitope within the internal region of human PAI-1. Species sequence homology: dog, chimpanzee.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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