Anti -PAI-1 (Plasminogen Activator Inhibitor Type 1, SERPINE1, PAI, PAI1, PAI-1, PLANH1,
Serine (or Cysteine) Proteinase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor
Type 1), Member 1, Plasminogen Activator Inhibitor, Type I) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
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| PAI-1 (plasminogen activator inhibitor-1), otherwise known as SERPINE1, is a 45kD serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis. | | | Catalog # | P4256-34Q1 | | Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and VLDL (very-low-density lipoprotein). | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 0.25-1ug/ml | | Western Blot: 0.1-0.2ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder from PBS, pH 7.2. No preservative added. Labeled with Biotin. Reconstitute with 500ul sterile 40-50% glycerol, 0.1% BSA, PBS. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant human PAI-1. | | Specificity | Recognizes human PAI-1 (plasminogen activator inhibitor-1). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -PAI-1 (Plasminogen Activator Inhibitor Type 1, SERPINE1, PAI, PAI1, PAI-1, PLANH1, Serine (or Cysteine) Proteinase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1, Plasminogen Activator Inhibitor, Type I) (Biotin) |
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