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You are here:Home » Antibodies » Abs to Infectious Disease Malaria » Anti -Plasmodium falciparum MSP1 (P. falciparum, Malaria)

Anti -Plasmodium falciparum MSP1 (P. falciparum, Malaria)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Plasmodium falciparum is a protozoan parasite that causes malaria in humans. Malaria caused by P. falciparum has high mortality rates and is the most common in sub-Saharan Africa. The parasite is transmitted by Anopheles mosquitoes. Merozoites are the result of asexual reproduction of the parasite in the hepatocytes. They are released from hepatocytes and infected erythrocytes to infect other erythrocytes. MSP1 is the most abundant protein on the surface of merozoites and is involved in parasite invasion of the erythrocyte. It has long been considered a promising candidate for a vaccine against malaria. Some studies have shown that naturally acquired antibodies to a cleavage product of MSP1 can be linked to a reduced risk of clinical malaria.
Catalog #P4256-68K
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10F297
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenPlasmodium falciparum MSP1.
SpecificityRecognizes the merozoite surface protein 1 of Plasmodium falciparum.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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