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Anti -Platelet-derived Growth Factor Receptor, beta (Beta-type Platelet-derived Growth Factor Receptor, PDGF-R-beta, PDGFRB, PDGFR, CD140 Antigen-like Family Member B, CD140b, JTK12, PDGFR1)
Anti -Platelet-derived Growth Factor Receptor, beta (Beta-type Platelet-derived Growth
Factor Receptor, PDGF-R-beta, PDGFRB, PDGFR, CD140 Antigen-like Family Member B, CD140b,
JTK12, PDGFR1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Platelet-derived growth factor (PDGF) a potent mitogen, has been implicated as a regulator of cell proliferation during development and in wound healing and in the stimulation of cell growth. PDGF exerts it biological effects by binding with different affinities to two distinct cell surface receptors; the a-receptor and the b-receptor. PDGF Receptor b constitutes a subfamily among the protein tyrosine kinase receptors. Structurally the protein has an extracellular part organized in five immunoglobulin-like domains, and the intracellular part containing tyrosine kinase domains with hydrophilic inserts of 100aa. | | | Catalog # | P4258-20V | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:1000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | 293 cells | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic non-phosphopeptide corresponding to human PDGF Receptor b around the phosphorylation site of tyrosine 751 (V-D-YP-V-P). | | Specificity | Recognizes human PDGF Receptor b. Species crossreactivity: rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | EC=2.7.10.1 |
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