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Platencin
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| Platencin is a more potent analogue of Platensimycin also discovered from a strain of Streptomyces platensis. Platencin shows potent in vivo efficacy without any observed toxicity. Platencin targets two essential proteins, -ketoacyl-acyl carrier protein (ACP) synthase II (FabF) and III (FabH) whereas platensimycin targets only FabF. | | | Catalog # | P4262 | | Source | Platencin | | Molecular Weight | ~425.2 | | Solubility | Soluble in ethanol, methanol, DMF or DMSO. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 869898-86-2 | | Molecular Formula | C24H27NO6 | | Molecular Weight | 425.2 | | Source | Streptomyces sp. MST-AS5989 | | Purity | 95% by HPLC | | Form | Supplied as a light tan solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
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