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You are here:Home » Biochemicals » Biochem-Antibiotics » Pleuromutilin (Drosophilin B, Antibiotic A 40104C)

Pleuromutilin (Drosophilin B, Antibiotic A 40104C)


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Pleuromutilin is a diterpene produced by several species of basidomycetes, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin.
Catalog #P4270-90
Source Pleurotus sp. MST-FP2115A
Apperance White solid
Solubility Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number125-65-5
Molecular FormulaC22H34O5
Molecular Weight378.5
SourcePleurotus sp. MST-FP2115A
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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