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Pleuromutilin (Drosophilin B, Antibiotic A 40104C)
Pleuromutilin (Drosophilin B, Antibiotic A 40104C)
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| Pleuromutilin is a diterpene produced by several species of basidomycetes, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin. | | | Catalog # | P4270-90 | | Source | Pleurotus sp. MST-FP2115A | | Apperance | White solid | | Solubility | Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | 125-65-5 | | Molecular Formula | C22H34O5 | | Molecular Weight | 378.5 | | Source | Pleurotus sp. MST-FP2115A | | Purity | ~95% | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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