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Abs to Plexin, Semaphorin
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Anti -Plexin A2 (PLXNA2, Plex 2, Plexin-2, KIAA0463)
Anti -Plexin A2 (PLXNA2, Plex 2, Plexin-2, KIAA0463)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E B |
|
| Plexin A2 (also OCT) is 220-230kD member of the Plexin A subfamily, Plexin family of proteins. It is found on cerebellar granule cells, sensory neurons, and cardiac neural crest cells. It participates in cell migration and axon guidance, and does so by serving as a receptor for Semaphorin 6A and B, and as a co-receptor with Neuropilin-1 for Semaphorin 3A and C. Mature mouse Plexin A2 is an 1860aa type I transmembrane glycoprotein. It contains a 1203aa extracellular domain (ECD) and a 636aa cytoplasmic region. The ECD contains one Sema-domain (aa40-481), three PSI domains (aa500-845) and four IPT regions (aa848-1226). There is one alternate start site 10 aa upstream of the standard start site. Over (aa25-1227), mouse Plexin A2 is 96% aa identical to human Plexin A2. | | | Catalog # | P4271-14B | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Direct ELISA: 0.5-1ug/ml | | Western Blot: 2ug/ml | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Myeloma cells with B cells from Balb/c mice. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 11D24 | | Host | Rat | | Source | Mouse | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant corresponding to mouse Plexin A2 expressed in CHO cells (P70207). | | Specificity | Recognizes mouse Plexin A2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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