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You are here:Home » Antibodies » Antibodies-Plexin, Semaphorin » Anti -PLXNB1 (Plexin B1, KIAA0407, MGC149167, PLXN5, Semaphorin Receptor SEP, SEP) (APC)

Anti -PLXNB1 (Plexin B1, KIAA0407, MGC149167, PLXN5, Semaphorin Receptor SEP, SEP) (APC)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Plexin B1 is a 300kD member of the B subfamily, plexin family of semaphorin receptors. Mature human Plexin B1 is a 2116aa type I transmembrane (TM) glycoprotein that contains a 1471aa extracellular domain (ECD) and a 612aa cytoplasmic region. The ECD contains one semaphorin domain, two PSI domains, and three IPT repeats. The ECD is cleaved into two subunits, a 200kD A-chain (aa20-1305) and a 100kD TM B-chain. The subunits are nondisulfide-linked and generate a high-affinity receptor. Plexin B1 is a receptor for CD100/Sema4D. It forms a receptor complex with neuropilins, MET, and EGFR2. Multiple splice variants are known. One shows a deletion of aa689-871. A second shows a 53aa substitution for aa677-2135. And a third shows a 53aa substitution for the 53aa between aa677-729. Over aa35-150, human Plexin B1 is 90% and 97% aa identical to dog and mouse Plexin B1, respectively.
Catalog #P4271-28A
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaFusion of a mouse myeloma with B cells obtained from a mouse immunized with NS0 cells transfected with human Plexin B1.
Clone TypeMonoclonal
Clone No10K23
Concentration100 Tests/ml
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0 cells transfected with human Plexin B1 (aa1-2135; Accession #O43157, isoform 1).
SpecificityRecognizes human Plexin B1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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