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You are here:Home » Antibodies » Abs to Myelin » Anti -Peripheral Myelin Protein 22, CT (PMP22, PMP-22, Growth Arrest-specific Protein 3, GAS-3, GAS3)

Anti -Peripheral Myelin Protein 22, CT (PMP22, PMP-22, Growth Arrest-specific Protein 3,
GAS-3, GAS3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
PMP22 is a major component of myelin expressed in the compact portion of essentially all myelinated fibers in the peripheral nervous system and is produced predominantly by Schwann cells. Studies in injured nerve suggested a role during Schwann cell growth and differentiation. PMP22 is expressed in cranial nerves but not in the mature central nervous system. Studies suggest a possible role of the PMP22 gene in the development of neoplasia in patients with neurofibromatosis and in the myelin degenerative Charcot-Marie-Tooth disease linked to chromosome 17p.
Catalog #P4305-04B
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human PMP22 at C-terminal (KLH).
SpecificityRecognizes human PMP22.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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