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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -PMP70 (Peroxisomal Membrane Protein 70, 70kD Peroxisomal Membrane Protein, ABC43, ABCD3, ABCD3 Protein, ATP-binding Cassette Sub-family D (ALD) Member 3, Peroxisomal Membrane Protein 1, PXMP1)

Anti -PMP70 (Peroxisomal Membrane Protein 70, 70kD Peroxisomal Membrane Protein, ABC43,
ABCD3, ABCD3 Protein, ATP-binding Cassette Sub-family D (ALD) Member 3, Peroxisomal
Membrane Protein 1, PXMP1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
Peroxisomes are single membrane organelles which are involved with many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including, phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via beta-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum's disease. Peroxisomal Membrane Protein 70 (PMP 70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal beta-oxidation enzymes.
Catalog #P4305-91C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.2-0.6ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Kidney lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to CPDGREDQKRKGISD, from the internal region of the protein sequence according to NP_002849.1.
SpecificityRecognizes human ABCD3. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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