Anti -PNPLA2 (PEDFR, Patatin-like phospholipase domain containing 2, 1110001C14Rik,
Adipose triglyceride lipase, ATGL, Calcium-independent phospholipase A2, desnutrin,
Desnutrin, DESNUTRIN, DKFZp667M109, FP17548, IPLA2-zeta, Patatin-like phospholipase
domain-co
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
E B IH |
|
| PEDF R (Pigment epithelium derived factor receptor; also ATGL, PNPLA2 and desnutrin) is a 55kD member of the PNPLA family of proteins. It is expressed in adipocytes, hepatocytes, skeletal muscle and pigment epithelium. PEDF R specifically hydrolyses triglycerides, releasing long-chain fatty acids. Mouse PEDF R is described as being a 486aa type II transmembrane | | | (TM) protein. Its TM segment is stated to span aa9-29. Alternatively, it may have a hydrophobic lipid-association domain between aa 267-295. It contains a palatin domain (aa10-179) with a conserved GxSxG enzymatic motif. There are multiple splice forms. Two show alternate start sites at Met57 and Met232, while two others show a deletion of aa163-196 and 253-308, | | | respectively. Over aa 62-253, mouse PEDF R shares 98% and 93% aa identity with rat and human PEDF R, respectively. | | | | | | Applications: | | | Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. | | | Catalog # | P4350-15 | | Recommended Dilution | Western Blot: 1.0ug/ml | | Immunohistochemistry: 5-15ug/ml detects PNPLA2 in cells and tissues | | Direct ELISA: 0.5-1.0ug/ml. The detection limit for recombinant mouse and recombinant human PNPLA2 is ~1ng/well | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | ~0.2mg/ml (after reconstitution) | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant corresponding to aa162-253 from mouse PNPLA2, expressed in E. coli (Q8BJ56). | | Specificity | Recognizes human PNPLA2. Species crossreactivity: mouse and rat | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -PNPLA2 (PEDFR, Patatin-like phospholipase domain containing 2, 1110001C14Rik, Adipose triglyceride lipase, ATGL, Calcium-independent phospholipase A2, desnutrin, Desnutrin, DESNUTRIN, DKFZp667M109, FP17548, IPLA2-zeta, Patatin-like phospholipase domain-co |
External Links
|
