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You are here:Home » Antibodies » Abs to Enzymes, Phospholipase » Anti -PNPLA6 (Patatin-like Phospholipase Domain Containing, NTE, Neuropathy Target Esterase, sws, SPG39, NTEMND, NTE, Patatin-like phospholipase domain containing 6)

Anti -PNPLA6 (Patatin-like Phospholipase Domain Containing, NTE, Neuropathy Target
Esterase, sws, SPG39, NTEMND, NTE, Patatin-like phospholipase domain containing 6)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
Catalog #P4350-19
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:64,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to C-YQGRQTSSIFEAAKQ, from the internal region of human PNPLA6 (NP_006693.3).
SpecificityRecognizes PNPLA6. Species sequence homology: human, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesNeuropathy target esterase, sws, SPG39, NTEMND, NTE, patatin-like phospholipase domain containing 6, PNPLA6


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