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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -POU Domain, Class 2, Transcription Factor 1 (POU2F1, POU Class 2 Homeobox 1, NF-A1, Octamer-binding Transcription Factor 1, OCT1, OCT-1, OTF1, OTF-1)

Anti -POU Domain, Class 2, Transcription Factor 1 (POU2F1, POU Class 2 Homeobox 1, NF-A1,
Octamer-binding Transcription Factor 1, OCT1, OCT-1, OTF1, OTF-1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Oct-1 is a 90kD transcription factor that binds to the octamer motif ATTTGCAT. This ubiquitous regulatory element is most conspicuous in B cells, where it is found in every immunoglobulin (Ig) promoter and in most Ig enhancers. In addition, Oct-1 binding also activates the promoters of the genes for some small nuclear RNAs (snRNA) and for histone H2B. Oct-1 protein is expressed in multiple tissues although some Oct-1 isoforms appear to be tissue specific and the homologous Oct-2 appears to the Oct proteins bind to DNA together with another protein transcription factor, octamer binding factor-1 (OBF-1), to form a ternary complex. Evidence suggests that regulation of Oct family transcription factors occurs at the level of phosphorylation.
Catalog #P5250-01F1
ApplicationsSuitable for use in Western Blot. Not suitable for Immunoprecipitation or Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 10ug/ml
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11n156
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 100ul PBS, pH 7.2, 50% glycerol.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to Oct-1.
SpecificityRecognizes human Oct-1. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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