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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -POU Domain, Class 3, Transcription Factor 2 (POU3F2, POUF3, Brain 2, Brain Specific Homeobox/POU Domain Protein 2, BRN2, BRN-2, N-Oct-3, Nervous System-specific Octamer-binding Transcription Factor N-Oct-3, Octamer Binding Transcription Factor 7, OCT7, OT

Anti -POU Domain, Class 3, Transcription Factor 2 (POU3F2, POUF3, Brain 2, Brain Specific
Homeobox/POU Domain Protein 2, BRN2, BRN-2, N-Oct-3, Nervous System-specific
Octamer-binding Transcription Factor N-Oct-3, Octamer Binding Transcription Factor 7,
OCT7, OT

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM]
Catalog #P5250-23A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1,000
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No11C592
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant protein corresponding to a portion of amino acids within aa1-68 of human POU3F2.
SpecificityRecognizes human POU3F2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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