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Anti -PPARd, CT (Peroxisome Proliferator Activated Receptor, delta)
Anti -PPARd, CT (Peroxisome Proliferator Activated Receptor, delta)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| PPARd (Peroxisome Proliferator Activated Receptor, delta) is a ubiquitously expressed member of the nuclear hormone receptor subfamily of transcription factors, which regulates peroxisome numbers and influences fatty acid metabolism. The transcriptional activity of PPAR delta depends upon its interaction with retinoid X receptor (RXR), which together bind to peroxisome proliferator-response elements (PPREs) within the promoter region of target genes, in the presence of cofactors. The interaction of PPAR delta with NCoR (nuclear receptor corepressor) and SMRT (silencing mediator for retinoid and thyroid hormone receptor), results in repression of PPAR delta transactivation. | | | Catalog # | P5505-02D | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilutions | ELISA: 1:16,000 | | Western Blot: 0.3-1ug/ml. Detects a band of ~50kD in Jurkat T cell lysates. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a TBS, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by affinity chromatography. | | Immunogen | Peptide corresponding to CHPLLQEIYKDMY from the C-Terminal region of PPARd (NP_006229.1). Species Sequence Homology: mouse, rat, porcine, chicken | | Specificity | Recognizes an epitope within the C-terminal (CT) region of isoform 1 of human PPARd. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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