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You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -PPARg (Peroxisome Proliferator Activated Receptor gamma, PPAR-gamma, PPARG1, PPARG2, PPARG3, HUMPPARG, Nuclear Receptor Subfamily 1 Group C Member 3, NR1C3, PAX8/PPARG Fusion Gene)

Anti -PPARg (Peroxisome Proliferator Activated Receptor gamma, PPAR-gamma, PPARG1, PPARG2,
PPARG3, HUMPPARG, Nuclear Receptor Subfamily 1 Group C Member 3, NR1C3, PAX8/PPARG Fusion
Gene)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Peroxisome proliferator-activated receptors (PPAR) are members of the steroid nuclear receptor superfamily (1). The mammalian PPARs include three subtypes PPARalpha, PPARbeta, and PPARgamma. PPARs have been found to regulate fatty acid oxidation, fat cell development, lipoprotein metabolism, and glucose homeostasis (2). Recent studies have found that PPARs can affect the pathogenesis and development of tumors (3). PPARgamma and PPARbeta have been specifically implicated in tumorigenesis (3). PPARalpha is the focus of research studying its function in fatty acid beta-oxidation, lipid metabolism, and vascular inflammation (4). PPARbeta also plays a key role in the activation of keratinocytes during the inflammatory reaction associated with a skin injury (5). Of the three subtypes of PPARs, PPARgamma is the most widely studied. PPARgamma has been implicated in various human chronic diseases such as diabetes mellitus, atherosclerosis, rheumatoid arthritis, inflammatory bowel disease, and Alzheimer s disease (6).
Catalog #P5505-06D
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:400
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in PBS, 0.1mg BSA, 0.1% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to the C terminus of human PPAR gamma. Cellular Localization: Nuclear.
SpecificityRecognizes both human PPARgamma1 and PPARgamma2.
Species CrossreactivityMouse, rat, bovine, chicken, canine and porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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