Anti -PPARd (Peroxisome Proliferator Activated Receptor, delta, PPAR-delta, Peroxisome
Proliferator-Activated Receptor beta, PPAR-beta, Nuclear Receptor Subfamily 1 Group C
Member 2, Nuclear Hormone Receptor 1, NUC1, Ppard, Nr1c2, Pparb) (Azide Free)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. [provided by RefSeq] | | | Catalog # | P5505-08C | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500-1:1,000 | | ELISA: 1ug/ml-3ng/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 11C594 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free). | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant protein corresponding to aa1-362 of human PPAR DELTA. | | Specificity | Recognizes human PPAR DELTA. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -PPARd (Peroxisome Proliferator Activated Receptor, delta, PPAR-delta, Peroxisome Proliferator-Activated Receptor beta, PPAR-beta, Nuclear Receptor Subfamily 1 Group C Member 2, Nuclear Hormone Receptor 1, NUC1, Ppard, Nr1c2, Pparb) (Azide Free) |
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