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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -PRDM14 (PR Domain Zinc Finger Protein 14, PR Domain-containing Protein 14)

Anti -PRDM14 (PR Domain Zinc Finger Protein 14, PR Domain-containing Protein 14)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
PRDM14 is an approximately 65kD transcriptional inhibitor that contains one histone methylating PR/SET domain (aa266-367) and six zinc finger repeats(aa400-568). PRDM14 is preferentially expressed in germ cells and undifferentiated embryonic stem cells in which it plays a central role in lineage specification, maintenance of pluripotency, and repression of somatic gene transcription. PRDM14 is up-regulated in breast cancer and lymphoblastic leukemia. Within (aa1- 201), human and mouse PRDM14 share 46% aa sequence identity.
Catalog #P5750-58A
ApplicationsSuitable for use in Direct ELISA, Western Blot.. Other applications not tested.
Recommended DilutionDirect ELISA: 0.5-1ug/ml
Western Blot: 2ug/ml
Optimal dilutions to be determined by the researcher.
HybridomaMyeloma cells with B cells from Balb/c mice.
Storage and Stability Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11D13
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to PRDM14 expressed in E. coli (Q9GZV8).
SpecificityRecognizes human PRDM14.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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