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Abs to Transcription Factors, Zinc (Ring) Finger
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Anti -PRDM14 (PR Domain Zinc Finger Protein 14, PR Domain-containing Protein 14)
Anti -PRDM14 (PR Domain Zinc Finger Protein 14, PR Domain-containing Protein 14)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| PRDM14 is an approximately 65kD transcriptional inhibitor that contains one histone methylating PR/SET domain (aa266-367) and six zinc finger repeats(aa400-568). PRDM14 is preferentially expressed in germ cells and undifferentiated embryonic stem cells in which it plays a central role in lineage specification, maintenance of pluripotency, and repression of somatic gene transcription. PRDM14 is up-regulated in breast cancer and lymphoblastic leukemia. Within (aa1- 201), human and mouse PRDM14 share 46% aa sequence identity. | | | Catalog # | P5750-58A | | Applications | Suitable for use in Direct ELISA, Western Blot.. Other applications not tested. | | Recommended Dilution | Direct ELISA: 0.5-1ug/ml | | Western Blot: 2ug/ml | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Myeloma cells with B cells from Balb/c mice. | | Storage and Stability Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 11D13 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | | Immunogen | Recombinant corresponding to PRDM14 expressed in E. coli (Q9GZV8). | | Specificity | Recognizes human PRDM14. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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