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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -PRDM16 (PR Domain Zinc Finger Protein 16, PR Domain-containing Protein 16, Transcription Factor MEL1, MDS1/EVI1-like Gene 1, KIAA1675, MEL1, PFM13)

Anti -PRDM16 (PR Domain Zinc Finger Protein 16, PR Domain-containing Protein 16,
Transcription Factor MEL1, MDS1/EVI1-like Gene 1, KIAA1675, MEL1, PFM13)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
PRDM16, also known as Mel1, is a zinc finger protein that plays a role in the differentiation of brown adipose tissue, which plays a role in dissipating heat in response to cold or excess feeding. PRDM16 works together with CEBPB to regulate the differentiation of myoblastic precursors into brown adipose cells. PRDM16 is also a repressor of TGF beta signalling, interacting with SKI to promote the recruitment of the SMAD3-HDAC1 complex to the promoter of TGF beta target genes.
Catalog #P5750-80B
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-TSESGAFHPINHL, from PRDM16, at C-terminal (NP_071397.2, NP_955533.1).
SpecificityRecognizes PRDM16. Species sequence homology: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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