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You are here:Home » Antibodies » Abs to Albumin » Anti -Prealbumin (PALB, Amyloid Polyneuropathy, Amyloidosis I, ATTR, Dysprealbuminemic Euthyroidal Hyperthyroxinemia, Dystransthyretinemic Hyperthyroxinemia, HsT2651, Prealbumin Amyloidosis Type I, Senile Systemic Amyloidosis, TBPA, Transthyretin, TTR, TTR Prot

Anti -Prealbumin (PALB, Amyloid Polyneuropathy, Amyloidosis I, ATTR, Dysprealbuminemic
Euthyroidal Hyperthyroxinemia, Dystransthyretinemic Hyperthyroxinemia, HsT2651, Prealbumin
Amyloidosis Type I, Senile Systemic Amyloidosis, TBPA, Transthyretin, TTR, TTR Prot

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH FC
Prealbumin (TTR) is a hormone-binding protein that participates in the plasma transport of both thyroxine and retinol (vitamin A). Prealbumin concentrations are disproportionately high in human ventricular cerebrospinal fluid (CSF). It is reported to be either selectively transported across or synthesized within the blood-CSF barrier (3). Over 80 different disease-causing mutations in prealbumin have been reported. The vast majority is inherited in an autosomal dominant manner and is related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. A small portion of prealbumin mutations are apparently non-amyloidogenic (4). The human amyloid disorders, familial amyloid polyneuropathy, familial amyloid cardiomyopathy and senile systemic amyloidosis, are caused by insoluble prealbumin fibrils (2).
Catalog #P6000-06A
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:5000
Immunohistochemistry: 1:100-1:250
Flow Cytometry: 1:80
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9E463
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50 mM Tris-Glycine, pH 7.4, 0.15 M sodium chloride, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues in human Prealbumin.
SpecificityRecognizes human Prealbumin
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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