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You are here:Home » Antibodies » Abs to Albumin » Anti -Prealbumin (PALB, ATTR, HsT2651, TBPA, Transthyretin, TTR)

Anti -Prealbumin (PALB, ATTR, HsT2651, TBPA, Transthyretin, TTR)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
TTR encodes transthyretin, a circulating and abundant tetramer that functions as a carrier protein of thyroid hormone and retinol binding protein. Transthyretin(TTR) is mainly produced in the liver, but also in the brain and eye. Mutations in TTR cause the protein to dissociate into monomers that after misfolding assemble into amyloid fibrils deposits in a diversity of organs. TTR is also the only gene known to be associated with familial TTR amyloidosis. Familial transthyretin (TTR) amyloidosis is characterized by a slowly progressive peripheral sensorimotor neuropathy and autonomic neuropathy as well as non-neuropathic changes of cardiomyopathy, nephropathy, vitreous opacities, and CNS amyloidosis.
Catalog #P6000-13
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionsELISA: 1:500
Western Blot: 1:500-1:3000
Optimal dilutions to be determined by the researcher.
HybridomaFO myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No11C260
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide
PurityPurified by Protein G affinity chromatography
ImmunogenRecombinant protein corresponding to aa21-147 from human Prealbumin expressed in E. coli (NP_000362).
SpecificityRecognizes human Prealbumin. Species Crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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