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You are here:Home » Antibodies » Abs to Kallikrein » Anti -Prekallikrein (Plasma Prekallikrein, Plasma Kallikrein, Fletcher Factor, Kininogenin, KLKB1, KLK3)

Anti -Prekallikrein (Plasma Prekallikrein, Plasma Kallikrein, Fletcher Factor,
Kininogenin, KLKB1, KLK3)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Serum E
Prekallikrein is a single-chain, glycoprotein (MW 88000) present in inactive form in plasma,
pancreas and intestine. Prekallikrein is activated to kallikrein by Factor XIIa which in turn
results from activation of Factor XII by prekallikrein combined with Factor XII and high molecular-
weight kininogen (HMWK). It releases kinins from the low-molecular-weight and the
high-molecular-weight kininogen. Plasma kallikrein is present in two slightly different forms. This corresponds with two different forms of kallikrein after prekallikrein has been activated by Factor XIIa.
Catalog #P6201-01
ApplicationsSuitable for use in ELISA, Electroimmunodiffusion, Immunoelectrophoresis and Radial Immunodiffusion. Other applications not tested.
Recommended DilutionElectroimmunodiffusion (Laurell): 1-2% agarose gel, depending on the test arrangement.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder. Preservative free. Reconstitute with 1ml sterile ddH2O. Dilute further in PBS, pH 7.2.
PuritySerum
ImmunogenPrekallikrein isolated and purified from pooled human plasma
SpecificityRecognizes human Prekallikrein. May react with inactive plasma prekallikrein and active kallikrein. Does not react with Factor XI. Does not crossreact with any other human plasma proteins as tested in gel diffusion techniques. Species Crossreactivity: Monkey
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=3.4.21.34


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