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You are here:Home » Molecular Biology » MB-Enzymes, Phosphatase » PRL-3, Recombinant Human (Protein tyrosine phosphatase type IVA 3)

PRL-3, Recombinant Human (Protein tyrosine phosphatase type IVA 3)

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Specifications

Protein tyrosine phosphatase type IVA 3 (PRL-3), as known as PTP4A3, belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) that remove phosphate modifications from tyrosine residues on proteins. This protein enhances cell proliferation, cell motility and invasive activity. High levels of PRL-3 expression are associated with tumorigenesis and metastasis, thus it is overexpressed in metastatic colorectal, ovarian, liver and skin cancers. Recombinant human PRL-3, fused to His-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography.
Catalog #P9003-70B
SourceRecombinant human PRL-3, aa1-173, His-tagged, expressed in E. coli
AA SequenceMGSSHHHHHH SSGLVPRGSH MARMNRPAPV EVSYKHMRFL ITHNPTNATL STFIEDLKKY GATTVVRVCE VTYDKTPLEK DGITVVDWPF DDGAPPPGKV VEDWLSLVKA KFCEAPGSCV AVHCVAGLGR APVLVALALI ESGMKYEDAI QFIRQKRRGA INSKQLTYLE KYRPKQRLRF
KDPHTHKTRC CVM
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight21.6kD
SourceE.coli
Purity~95% by SDS-PAGE Purified by immunoaffinity chromatography.
Concentration~1mg/ml
FormSupplied as liquid in 20 mM Tris-HCl buffer, pH8.0, 2 mM EDTA, 1 mM DTT, 10% glycerol
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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