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Abs to Enzymes, Methyltransferase
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Anti -PRMT6 (Protein Arginine Methyltransferase 6, Protein Arginine N-methyltransferase 6, FLJ10559, Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-like Protein 6, HMT1 hnRNP Methyltransferase-like 6, HRMT1L6)
Anti -PRMT6 (Protein Arginine Methyltransferase 6, Protein Arginine N-methyltransferase 6,
FLJ10559, Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-like Protein 6, HMT1
hnRNP Methyltransferase-like 6, HRMT1L6)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| PRMT6 severely impairs the function of HIV-1 Rev. | | | PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication. | | | Catalog # | P9004-30C | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Tris-citrate/phosphate buffer, pH 7 to 8 | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope recognized maps to a region between residue 325 and the C-terminus (residue 375) of human Protein Arginine Methyltransferase 6 using the numbering given in entry AAK85733.1 (GeneID 55170). | | Specificity | This antibody is specific to the human PRMT6 protein. Species Crossreactivity: Human. Other species have not been tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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