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You are here:Home » Antibodies » Abs to Receptors » Anti -Progesterone Receptor (PgR)

Anti -Progesterone Receptor (PgR)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E IH
Catalog #P9007-15E1
Human PgR exists in two forms 116kD (B-form) and 81kD (A-form). It acts as ligand activated transcription factor to regulate expression of the target genes. Null mutation in PgR gene leads to pleiotrophic reproductive abnormalities.
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Formalin-fixed, paraffin-embedded): 1:50-1:100 for 20 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at RT for 20 minutes.
Optimal dilutions to be determined by the researcher.
Positive ControlT47D cells, Breast carcinoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in PBS, pH 7.6, 0.2% BSA, 15mM sodium azide.
PurityPurified
ImmunogenRecombinant protein encoding human progesterone receptor aa412-526. Cellular Localization
SpecificityRecognizes human Progesterone Receptor.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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