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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Prohibitin (PHB)

Anti -Prohibitin (PHB)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IH IC IF
Prohibitin is an evolutionarily conserved protein located in the inner membrane of mitochondria. Prohibitin shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization and tumor suppression. Prohibitin is also sometimes found in the nucleus in certain cells types and cell states.
Catalog #P9007-51B
Cellular Localization Cytoplasmic
ApplicationsSuitable for use in Immunofluorescence, Western Blot, Immunohistochemistry (Fr) (paraffin-embedded sections) and Immunocytochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50%glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9A433
HostMouse
SourceRat
ConcentrationAs reported
Form1% BSA
PurityPurified
ImmunogenBALB/C mice were injected with purified recombinant rat prohibitin protein.
SpecificityThis antibody is specific to 30kD protein known as Prohibitin. Prohibitin is an evolutionarily conserved protein located in the innermembrane of mitochondria. Prohibitin shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization and tumor suppression. This antibody crossreacts with mouse, rat and porcine. Species Crossreactivity: This antibody is reactive against human, mouse, rat and porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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