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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Prohibitin

Anti -Prohibitin

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Prohibitin is located in the inner membrane of the mitochondria. It is expressed in a variety of tissues. Prohibitin inhibits DNA synthesis and plays a role in regulating negative cell proliferation. It may also be a tumor suppressor. Mutations in prohibitin have been linked to sporadic breast cancer. However, it is not yet clear whether it is the protein itself or the associated mRNA that exhibits these effects. Prohibitin may also play a role in regulating mitochondrial respiration activity and in aging.
Catalog #P9007-51D
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.05-0.2ug/ml
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide within residues 100-150 of human prohibitin protein (Swiss Prot: P35232).
SpecificityRecognizes endogenous levels of human prohibitin protein. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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