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You are here:Home » Antibodies » Antibodies-Membrane Proteins » Anti -Prohibitin

Anti -Prohibitin


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Prohibitin is believed to be a negative regulator of cell proliferation and may also act as a tumor suppressor. Mutations in prohibitin have been linked to sporadic breast cancer. Prohibitin inhibits DNA synthesis and plays a role in proliferation regulation. As yet, it is unclear if it is the protein or the mRNA that exhibits these effects. Prohibitin may play a role in regulating mitochondrial respiration activity and aging. Prohibitin is located at the inner mitochondrial membrane and is widely expressed in various tissues.
Catalog #P9007-51E
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.05-0.2ug/ml
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a lyophilized powder in PBS, pH 7.4, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide (KLH). derived from within residues 50-100 of human prohibitin (Swiss Prot: P35232).
SpecificityRecognizes endogenous levels of human prohibitin protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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