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You are here:Home » Antibodies » Antibodies-Membrane Proteins » Anti -Prohibitin (PHB)

Anti -Prohibitin (PHB)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IF
Prohibitin is an evolutionarily conserved protein that has anti-proliferative activity. Prohibitin is a 30kD, post-synthetically modified protein found in the inner membrane of mitochondria and on the plasma membrane of B cells. It mediates B cell mutation. Prohibitin controls cell cycle in both transcriptional and post-translational mechanisms. Prohibitin is a potential tumor suppressor. Prohibitin gene mutations are correlated with the breast cancer development and/or progression in over 80 the cell lines analyzed.
Catalog #P9007-51N
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionImmunofluorescence: 5-10ug/ml
Western Blot: 0.5-4ug/ml
Immunoprecipitation: 10-20ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa256 from human Prohibitin.
SpecificityRecognizes human Prohibitin. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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