Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Receptors » Anti -Prolactin Receptor (PRLR, PRL-R, PRL Receptor)

Anti -Prolactin Receptor (PRLR, PRL-R, PRL Receptor)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH IC
Prolactin (PRL) is a hormone involved in a variety of important functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor, a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40kD to 100kD. The PRL receptor consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.
Catalog #P9009-53A
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1ug/ml detected PRLR on NB2 cell lysates.
Immunohistochemistry (Paraffin): Staining of PRL receptor in NB2 cells yields a staining pattern consistent with cytoplasmic vesicular staining.
Immunocytochemistry: 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9A441
HostMouse
SourceRat
Concentration~1mg/ml
FormSupplied as a lyophilized powder. No preservative added. Reconstitute with 100ul sterile PBS.
PurityPurified by affinity chromatography
ImmunogenPurified rat liver PRL receptor.
SpecificityRecognizes the rat Prolactin Receptor at ~42kD. Does not crossreact with the Growth Hormone receptor.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links