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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -PROP1 (PROP Paired-like Homeobox 1)

Anti -PROP1 (PROP Paired-like Homeobox 1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
PROP1 has both DNA-binding and transcriptional activation ability. Its expression leads to ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes, and caudomedial thyrotropes. Inactivating mutations in PROP1 result in deficiencies of luteinizing hormone (LH; MIM 152780), follicle-stimulating hormone (FSH; MIM 136530), growth hormone (GH; MIM 139250), prolactin (PRL; MIM 176760), and thyroid-stimulating hormone (TSH; MIM 188540). See combined pituitary hormone deficiency-2 (CPHD2; MIM 262600).
Catalog #P9035
ApplicationsSuitable for use in ELISA. Other applications have not been tested.
Recommended Dilutions
Peptide ELISA Titer: 1:32,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by peptide affinity chromatography.
ImmunogenSynthetic peptide corresponding to AERRRQAEKPKKGR-C, from the N-Terminus of human PROP1 (NP_006252.2).
SpecificityRecognizes PROP1. Species sequence homology: human
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesprophet of Pit1, paired-like homeodomain transcription factor, OTTHUMP00000161487, PROP paired-like homeobox 1, PROP1, Pituitary-specific homeodomain factor, PROP-1


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