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You are here:Home » Antibodies » Abs to Enzymes » Anti -Proprotein Convertase Subtilisin Kexin 9 (Proprotein Convertase Subtilisin/kexin Type 9, PCSK9, FH3, Hypercholesterolemia Autosomal Dominant 3, HCHOLA3, Neural Apoptosis Regulated Convertase 1, NARC1, NARC-1, PC9, Proprotein Convertase PC9, PSEC0052, Subt

Anti -Proprotein Convertase Subtilisin Kexin 9 (Proprotein Convertase Subtilisin/kexin
Type 9, PCSK9, FH3, Hypercholesterolemia Autosomal Dominant 3, HCHOLA3, Neural Apoptosis
Regulated Convertase 1, NARC1, NARC-1, PC9, Proprotein Convertase PC9, PSEC0052, Subt

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
Catalog #P9052-40A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1600
Western Blot: 0.3ug/ml. In McA cell lysates, two bands are observed at ~73 and 60kD representing unprocessed and processed protein.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide CRSRHLAQASQELQ, representing the C-Terminus of the human protein sequence according to NP_777596.2.
SpecificityRecognizes human PCSK9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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