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You are here:Home » Antibodies » Abs to Prostaglandins » Anti -PTGER3 (Prostaglandin E2 Receptor EP3 Subtype, PGE Receptor EP3 Subtype, PGE2 Receptor EP3 Subtype, PGE2-R, Prostanoid EP3 Receptor)

Anti -PTGER3 (Prostaglandin E2 Receptor EP3 Subtype, PGE Receptor EP3 Subtype, PGE2
Receptor EP3 Subtype, PGE2-R, Prostanoid EP3 Receptor)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems.
Catalog #P9053-26M7
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:2000
Western Blot: 1-3ug/ml, observed in human adipose, kidney, pancreas and placenta lysates on ~55kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to KLLREPCSVQLS, from human PTGER3, at C-terminal of the protein (NP_000948.2, NP_942005.2, NP_942006.1).
SpecificityRecognizes human PTGER3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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