Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Prostaglandins » Anti -Prostaglandin Dehydrogenase 1 (HPGD, PGDH1, 15-PGDH, hydroxyprostaglandin dehydrogenase 15-(NAD), Prostaglandin dehydrogenase 1)

Anti -Prostaglandin Dehydrogenase 1 (HPGD, PGDH1, 15-PGDH, hydroxyprostaglandin
dehydrogenase 15-(NAD), Prostaglandin dehydrogenase 1)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
15-PGDH (15-hydroxyprostaglandin dehydrogenase NAD-linked; also HPGD) is a 28-29kD member of the short-chain non-metalloenzyme family of dehydrogenases. It is widely expressed, and antagonizes COX-2 by catalyzing the oxidation of 15-OH prostaglandin to metabolically inactive 15-keto metabolites. Human 15-PGDH is 266aa in length. A Tyr at position #151 serves as a proton acceptor, and a Ser at #138 binds substrate. 15-PGDH functions as a nondisulfide-linked homodimer. There is one alternate splice form that shows a 12aa substitution for aa167-266. Full-length human 15-PGDH shares 88% aa identity with mouse 15-PGDH.
Catalog #P9053-27C5
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.5-1.0ug/ml
Western Blot: 1.0ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a lyophilized powder in 0.2um sterile-filtered solution, PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant human 15-hydroxyprostaglandin dehydrogenase aa1-266; P15428 (E. coli).
SpecificityRecognizes human 15-PGDH.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links