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You are here:Home » Antibodies » Abs to Prostaglandins » Anti -Prostaglandin I Synthase (PGIS)

Anti -Prostaglandin I Synthase (PGIS)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Prostaglandin I Synthase catalyzes the isomerization of PGH2 to PGI2 (prostacyclin). PGI2 is a potent vasodilator and inhibitor of platelet aggregation. PGIS is a membrane-bound hemoprotein localized primarily in endothelial cells. The cloned bovine and human enzymes contain 500aa and calculated molecular mass of 56,629 and 57,103, respectively. Northern blot analysis reveals that the mRNA for PGIS is expressed in a wide variety of human tissues and is particularly abundant in ovary, heart, skeletal muscle, prostate and lung.
Catalog #P9053-39
Applications
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationAs Reported
FormSupplied as a lyophilized powder from TBS. Reconstitute with 100ul sterile ddH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa475-490, PEFDLSRYGFGLMQPE from mouse PGIS.
SpecificityRecognizes mouse PGIS. Species Crossreactivity: human, bovine, ovine and rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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