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You are here:Home » Antibodies » Abs to Proteasomes » Anti -Proteasome beta 4 Subunit (PSMB4, Proteasome Subunit HsN3, Macropain beta Chain, Proteasome Chain 3, Multicatalytic Endopeptidase Complex beta Chain)

Anti -Proteasome beta 4 Subunit (PSMB4, Proteasome Subunit HsN3, Macropain beta Chain,
Proteasome Chain 3, Multicatalytic Endopeptidase Complex beta Chain)

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Specifications

Clone Host Grade Applications
Polyclonal Chicken Affinity Purified E B
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
Catalog #P9076-14
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgY
HostChicken
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-264
SpecificityRecognizes human Proteasome beta 4 Subunit. Species Crossreactivity: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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