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Abs to Proteasomes
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Anti -Proteasome beta 4 Subunit (PSMB4, Proteasome Subunit HsN3, Macropain beta Chain, Proteasome Chain 3, Multicatalytic Endopeptidase Complex beta Chain)
Anti -Proteasome beta 4 Subunit (PSMB4, Proteasome Subunit HsN3, Macropain beta Chain,
Proteasome Chain 3, Multicatalytic Endopeptidase Complex beta Chain)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Chicken |
Affinity Purified |
E B |
|
| The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. | | | Catalog # | P9076-14 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000-1:2000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgY | | Host | Chicken | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS, pH 7.2. No preservative added. Glycerol free. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa1-264 | | Specificity | Recognizes human Proteasome beta 4 Subunit. Species Crossreactivity: Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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