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You are here:Home » Antibodies » Abs to Proteasomes » Anti -PSMB10 (Proteasome Subunit beta Type-10, Proteasome Subunit beta-2i, Proteasome MECl-1, Macropain Subunit MECl-1, Multicatalytic Endopeptidase Complex Subunit MECl-1, Low Molecular Mass Protein 10, LMP10, MECL1) (Azide Free)

Anti -PSMB10 (Proteasome Subunit beta Type-10, Proteasome Subunit beta-2i, Proteasome
MECl-1, Macropain Subunit MECl-1, Multicatalytic Endopeptidase Complex Subunit MECl-1, Low
Molecular Mass Protein 10, LMP10, MECL1) (Azide Free)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IF
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq]
Catalog #P9076-20
ApplicationsSuitable for use in ELISA, Immunofluorescence, and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1ug/ml-3ng/ml
Western Blot: 1:500-1:1,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C604
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant protein corresponding to aa1-274 of human PSMB10.
SpecificityRecognizes human PSMB10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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