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Anti -Proteasome 19S, Subunit S5A (PSMD4)
Anti -Proteasome 19S, Subunit S5A (PSMD4)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| S5a(PSMD4) is a subunit of the 19S regulatory proteasome complex functioning in ubiquitinylated-protein targeting and degradation. S5a contains two polyubiquitin binding motifs (UIM) which bind multiubiquitin chains by hydrophobic interaction. In addition to ubiquitin, the UIM of S5a shows high affinity to a ubiquitin-like domain present in many proteins. S5a binds to these types of protein directly and mediates their targeting to the proteasome for degradation. | | | Catalog # | P9078-25B | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Molecular Weight | 49kD | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. | | Purity | Purified by Protein A and immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to residues surrounding Gly344 of human S5a/PSMD4 protein (KLH). | | Specificity | Detects endogenous levels of total human S5a/PSMD4 protein, 49kD. Species Crossreactivity: Monkey, mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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