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You are here:Home » Antibodies » Abs to Proteasomes » Anti -PSMD4, CT (26S Proteasome Non-ATPase Regulatory Subunit 4, 26S Proteasome Regulatory Subunit S5A, 26S Proteasome Regulatory Subunit RPN10, Multiubiquitin Chain-binding Protein, Antisecretory Factor 1)

Anti -PSMD4, CT (26S Proteasome Non-ATPase Regulatory Subunit 4, 26S Proteasome Regulatory
Subunit S5A, 26S Proteasome Regulatory Subunit RPN10, Multiubiquitin Chain-binding
Protein, Antisecretory Factor 1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSDM4 one of the non-ATPase subunits of the 19S regulator lid.
Catalog #P9078-25E
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionsELISA: 1:1000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to a corresponding to a portion of amino acids within aa355-384 at the C-terminal of human PSMD4, conjugated to KLH.
SpecificityRecognizes human PSMD4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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