Anti -PSMC4, CT (26S Proteasome AAA-ATPase Subunit RPT3, Tat-binding Protein 7, TBP-7,
MIP224, MB67-interacting Protein, Proteasome 26S Subunit ATPase 4, 26S Protease Regulatory
Subunit 6B, PSMC4, MIP224, TBP7)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH FC |
|
| The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMC4 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. | | | Catalog # | P9078-26E | | Applications | Suitable for use in ELISA, Flow Cytometry, Immunohistochemistry and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Flow Cytometry: 1:10-1:50 | | Immunohistochemistry (paraffin sections): 1:50-1:100 | | Western Blot: 1:100-1:500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide | | Purity | Purified by immunoaffinity chromatography | | Immunogen | KLH-conjugated synthetic peptide between aa389~418 in the C-terminal region of human PSMC4 | | Specificity | Recognizes human PSMC4 | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -PSMC4, CT (26S Proteasome AAA-ATPase Subunit RPT3, Tat-binding Protein 7, TBP-7, MIP224, MB67-interacting Protein, Proteasome 26S Subunit ATPase 4, 26S Protease Regulatory Subunit 6B, PSMC4, MIP224, TBP7) |
External Links
|
