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You are here:Home » Antibodies » Abs to Protein C » Anti -Protein C (Coagulation Factor XIV)

Anti -Protein C (Coagulation Factor XIV)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP
Coagulation factor XIV, also known as Protein C, has anti-coagulation activity by degrading factors VIIIa and Va, which are required for thrombin activation. Protein C deficiency results in hereditary thrombophilia, and a severe recessive form may result in massive thrombosis fatal to patient. The deduced amino acid sequence of human protein C predicts a signal peptide (aa 1-32), a propeptide (aa 33-42), and a mature chain (aa 43-461), which can be converted into two disulfide-linked chains (light: aa 43- 199 and heavy: aa 200-461). The amino acid sequence of human protein C is 99.8%, 80%, 70%, 69% and 54% identical to that of chimpanzee, canine, rat, mouse and chicken.
Catalog #P9102-27
ApplicationsSuitable for use in Western Blot, Immunopreciptiation and ELISA. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Immunopreciptiation: 25ug/ml
ELISA: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No7H185
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0-derived recombinant human Coagulation Factor XIV (aa43-461) Accession # NP_000303
SpecificityRecognizes human Coagulation Factor XIV.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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